Molecular Interactions between Tarantula Toxins and Low-Voltage-Activated Calcium Channels
نویسندگان
چکیده
منابع مشابه
Molecular Interactions between Tarantula Toxins and Low-Voltage-Activated Calcium Channels
Few gating-modifier toxins have been reported to target low-voltage-activated (LVA) calcium channels, and the structural basis of toxin sensitivity remains incompletely understood. Studies of voltage-gated potassium (Kv) channels have identified the S3b-S4 "paddle motif," which moves at the protein-lipid interface to drive channel opening, as the target for these amphipathic neurotoxins. Voltag...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep23894